Aureomycin provides trusted control and treatment of bovine respiratory disease (BRD) and bacterial enteritis, and control of anaplasmosis in beef cattle during high-risk periods.
Chlortetracycline is bacteriostatic and interferes with binding of the aminoacyl-tRNA to the acceptor site on the mRNA-ribosome complex, disabling protein synthesis and preventing normal function and growth. This can occur at concentrations as low as 0.125 times the minimum inhibitory concentration (MIC) — the lowest amount of antimicrobial required to inhibit bacterial growth — and at normal (37ºC) and febrile (41ºC) temperatures, suggesting chlortetracycline would likely be effective whether given before or after the development of a febrile response.
